Skip to main content

Do DHT-Blocking Shampoos Fight Hair Loss? We Asked the Experts, and the Answer Surprised Us

If you’re losing hair or going bald, you’re likely one of the thousands of people dealing with DHT, dihydrotestosterone, the main cause behind pattern baldness. But a DHT blocker shampoo might be able to help.

To learn a bit more about DHT and the potential benefits of the best DHT blocker shampoo, we reached out to Dr. Michele Green, a New York City-based cosmetic dermatologist, for her expertise.

Keep reading for the answers to frequently asked questions about DHT and hair loss, followed by some of our favorite hair loss products.


What Is DHT?

DHT, or dihydrotestosterone, is a hormone naturally produced by men and women that’s responsible for most male characteristics, such as facial and body hair, when present in high levels, Dr. Green told SPY. “DHT is a by-product of the conversion of testosterone by the enzyme 5-alpha-reductase as it travels through the body.”

How does DHT relate to balding and hair loss?

DHT harms hair growth by attaching to hair follicles and interrupting the active growth, or anagen, phase. “DHT can attach itself to receptors that are present on hair follicles, over time causing them to shrink and preventing active hair growth,” Dr. Green said. “By disrupting hair growth in the active growth phase, the hair is in a longer resting period than usual. This extended resting phase causes a gradual hair loss, ultimately leading to excessive hair loss and potentially even baldness.”

What are DHT blockers?

“DHT blockers work by preventing DHT from binding to receptors at the hair follicles. This prevents shrinkage of the hair follicles and allows hair to move through the growth cycle as it naturally should,” Dr. Green said.

Related Stories

What ingredients purport to block DHT?

Before we get into the ingredients, a disclaimer: Everything we’re about to list below has been linked to increased hair growth through at least one study (though not always on humans) and a bevy of anecdotal or clinical evidence.

However, none of them have been comprehensively studied, and the studies that do exist are often small in scale or not conducted in a way that scientists can conclusively link a particular ingredient to hair growth. Oftentimes, the ingredients are also studied as supplements as opposed to topical treatments. So though many of the following ingredients might help block DHT and promote hair growth, the science can’t quite say that definitively.

  • Saw palmetto: One two-year study showed that saw palmetto supplements did promote hair growth, though it wasn’t as effective as finasteride (and way more saw palmetto was required). Dr. Green also mentioned saw palmetto as one of the few treatments, alongside finasteride, that is known to promote hair growth.
  • Ketoconazole: An antifungal, ketoconazole is known to help with dandruff and scalp inflammation. Some evidence also suggests ketoconazole promotes hair follicle growth at a level comparable to minoxidil and also disrupts the formation of DHT.
  • Pumpkin seed oil: A double-blind study showed how a pumpkin seed oil supplement promotes hair growth in part due to its suspected role in disrupting DHT.
  • Caffeine: A small study suggested caffeine helped to lengthen hair, increase the amount of time that hair grows and support the development of keratin in hair. But, it’s not proven that caffeine actively fights hair loss, including loss due to DHT.
  • Green tea: A study on mice found that mice that consumed green tea in their drinking water showed “significant hair regrowth” over six months of treatment.
  • Pygeum: Pygeum, which comes from the African cherry tree, supplements proved to be mildly effective at treating benign prostatic hyperplasia (BPH), a condition that comes about through the same reaction that causes DHT. This suggests it could be a potential treatment for hair loss.
  • Rosemary extract: A study with mice used topical rosemary oil and found that it strongly inhibited the process that results in the formation of DHT.
  • Stinging nettle: Like pygeum, a study has shown nettle to be effective in treating symptoms related to BPH, leading some to suppose it may help block DHT. However, a study comparing finasteride to supplements containing nettle and saw palmetto found the supplements had no inhibitive effect on DHT.

Now that we know what DHT is, how it causes hair loss and what ingredients to look for, we have one note from Dr. Green before diving into the best DHT blocker shampoos. We wanted to know what she thought about DHT blocker shampoos and their efficacy.

The Truth About DHT-Blocking Shampoo

Though many shampoos claim to block DHT, and some may promote hair growth by improving blood flow to the scalp and increasing overall scalp health, she doesn’t think any shampoo claiming DHT benefits will be effective, saying, “There is no true DHT blocking shampoo available on the market.” (Emphasis added.)

That means you should be extremely skeptical of the big claims made by many common hair loss shampoos.

So if you’re suffering from hair loss, you should consider proven hair loss treatments to use alongside or in place of DHT blocker shampoos, given the tenuous evidence of their topical effectiveness.


The Top DHT-Blocking Hair Loss Shampoo

Now that you’re fully informed, check out some of the most popular DHT-blocker and hair loss shampoos below. While the experts are skeptical that the best DHT-blocking shampoos will perform as advertised, we do know some guys with thinning hair who swear by these hair loss products. Each shampoo contains some of the ingredients from above.

As with any new health product, we recommend consulting your doctor before trying something new. After all, if you’re desperate to turn the tide on your hair loss, you should be working with a hair loss expert anyway.


1. Pura d’Or Anti-Hair Thinning Shampoo


The Pura d’Or Anti-Hair Thinning Shampoo has been a longtime SPY favorite for its extraordinary cache of DHT-blocking ingredients. If there’s an ingredient that purports to block DHT and/or promote hair growth, you’ll find it in this shampoo, including saw palmetto, nettle extract, rosemary, pygeum, pumpkin seed, green tea and at least a dozen more. If you’re looking for the best DHT blocker shampoo, no other shampoo boasts nearly as many DHT-blocking ingredients as the Pura d’Or shampoo.

Lazy loaded image
Courtesy of Amazon


2. Hims Thickening Shampoo


For ongoing hair loss, subscribe to receive the Hims Thickening Shampoo every one to three months. Powered by saw palmetto to stem hair loss, this shampoo also promises to thicken up and moisturize existing hair to set your growth up for success. What’s also great about this option is you can subscribe to Hims finasteride and Hims minoxidil for a full-frontal assault on your balding spots.

Lazy loaded image
Courtesy of Hims


3. Botanical Green Care Hair Loss Therapy Thickening Shampoo


If Pura D’Or has the most DHT-blocking ingredients, the Botanical Green Care Hair Loss Therapy Thickening Shampoo has got to be a close second. With saw palmetto, nettle extract, green tea extract, pumpkin seed oil, rosemary oil and caffeine, in addition to other anecdotally supported DHT blockers, this shampoo is just chock full. But beyond DHT blockers, it’s just an overall good shampoo, with plenty of other great cleansing and hydrating ingredients.

Lazy loaded image
Courtesy of Amazon


4. Hair Restoration Laboratories Professional Strength Hair Restore Shampoo


The Hair Restoration Laboratories Professional Strength Hair Restore Shampoo has the DHT-blocking ingredients you need to help stem hair loss and promote hair growth. Pumpkin seed oil, caffeine, pygeum, green tea extract, saw palmetto, ketoconazole and more work together to try to block DHT while cleansing your hair and scalp.

Lazy loaded image
Courtesy of Amazon


5. Keeps Thickening Shampoo for Men


Not only does Keeps make a great DHT blocker shampoo, the Keeps Thickening Shampoo for Men, it pairs you with a doctor when you subscribe to make sure you have a professional in your corner to advise you on your hair growth journey. Green tea and saw palmetto handle the DHT while caffeine and biotin ensure the hair that’s there is as strong as it can be.

Lazy loaded image
Courtesy of Keeps


6. Shiny Leaf Biotin Shampoo


Though the Shiny Leaf Biotin Shampoo doesn’t boast as many DHT-blocking ingredients as other shampoos, it’s much more affordable and still has a few DHT blockers known to work, such as saw palmetto and green tea extract. Biotin does not block DHT on its own, but it strengthens hair and pairs well with actual DHT-blocking ingredients to deliver thicker and fuller hair over time.

Lazy loaded image
Courtesy of Amazon


The Best Anti-Aging Products for Men in 2021