The Best Acne Spot Treatments to Get Rid of That Persistent Pimple

best acne spot treatment

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We’ve all been there before: you wake up one morning to find an unsightly pimple that makes you wish you could crawl back in bed and reverse to the night before. Acne is never fun and is often very painful. Your first inclination might be to pop the zit yourself, but it’s best if you don’t, in order to prevent more infection and scarring. So, how do you tame the pesky pimple that won’t give up when you absolutely need to look your best? The best acne spot treatments, of course!

Yes, the good old-fashioned routine of washing your face regularly will help minimize your chances of a breakout. But, if you include medicated cleansers and serums, or cleansers and serums with natural exfoliants and moisturizers, then you only strengthen your chances of tackling the problem when it suddenly arises. 

When looking for the best acne spot treatment, there are a few things that you should consider. Two ingredients are salicylic acid and glycolic ccids, which help to penetrate your pores and clean the oil residue and other impurities from your skin that cause acne. Also, tea tree oil, aloe vera and various natural extracts are the most effective ingredients used in acne serums.

So, although there are many different ways to combat acne, we think that cleansers and serums will help you get the job done most of the time. In any case, we suggest that you run these options by your doctor first before you apply them to your skin and irritate the issue.

Below, we selected some of the best acne spot treatments available on Amazon. So, if you’re looking for a product that will heal your skin and not agitate it, we have you covered. These products will keep your face and body smooth and tackle any pesky pimples that pop up along the way.


1. DRMTLGY Acne Spot Treatment


This serum helps to reduce up to 85% of the oil that sits within your pores. The treatment contains 5% benzoyl peroxide to work deep within the pores and 5% glycolic acid to reduce the appearance of scarring. This fast-acting treatment can be used on all skin types and is also paraben and sulfate-free.

a bottle of drmtlgy acne spot treatment on a white background Image courtesy of Amazon


2. Avarelle Acne Absorbing Cover Patch


Developed in South Korea, the Avarelle Acne Absorbing Cover Patches are formulated for sensitive skin and are 100% vegan. They are made with hydrocolloid, which helps them to dry out pimples and heal the skin underneath. The patches also blend in with every skin tone, which helps everybody wearing a patch go incognito.

a packet of acne cover patches on a white background Image courtesy of Amazon


3. Ollie Belle Cover Dot Acne Care


Our E-Commerce Editor, Taylor Galla, tried out these acne dots from Ollie Belle and was pleasantly surprised with the results. Her chin pimple disappeared after only a day of using them, and they were relatively comfortable to wear while they went to work. The stick-on dots have tempered edges for comfort and stayed on even during sweaty workouts. Each patch is infused with hydrocolloid that absorbs pus and oil from blemishes without drying out the skin. They can be worn all night without causing irritation or leaving a scar. We highly recommend these for stubborn, one-off pimples that you want to get rid of quickly.

ollie belle acne care dots, acne spot treatment Courtesy of Ollie Belle


4. Neutrogena Rapid Clear Acne Spot Treatment


This popular option from Neutrogena uses 10% of maximum-strength benzoyl to help fight stubborn acne and prevent future breakouts. It is gentle enough for daily usage both morning and night. Neutrogena states that you could even start to see signs of this product working after just one day.

Neutrogena Rapid Clear Stubborn Acne Face Wash Amazon

5. Gold Mountain Beauty Drying Lotion


When you need a fast solution, try a drying lotion. The Gold Mountain Beauty Drying Lotion features Tibetan seaberry and salicylic acid to help brighten and exfoliate the skin while also fighting acne, fading scars, shrinking large pores, reducing inflammation and loosening blackheads. You should use this product overnight for the best results. When the product arrives, it will look as though the lotion has separated, but that’s how the product is supposed to look, so do not shake it! Apply this product to the affected areas with a cotton swab or another clean tool that helps with smooth application.

gold mountain beauty drying lotion jar on a white background Image courtesy of Amazon


6. Neutralyze Maximum Strength Acne Moisturizer Cream


The Maximum Strength Acne Moisturizer Cream from Neutralyze features 2% salicylic acid, 1% mandelic acid, nitrogen boost skincare technology and time-released B.H.A. and A.H.A. to help produce healthy skin cells and to exfoliate your skin. This moisturizing cream helps to reduce redness and irritation, which helps to improve your complexion. It has built-in technology that allows for the cream to reduce oil secretion and fine lines and wrinkles. This product also contains no parabens, sulfates or fragrances, making it appropriate for usage on various skin types.

Neutralyze Maximum Strength Acne Moisturizer Cream Amazon

7. COSRX Acne Pimple Master Patch 


If you’re a person who prefers a “no fuss” approach to fighting acne and pimples, then the COSRX Acne Pimple Master Patch is for you. The patch protects the area of concern while creating a moist environment to prompt quicker and easier healing. It comes in three sizes and works for various skin types. With one of the main ingredients used within the patches being A.D.F. hydrocolloid dressing, this product helps you to see a visible change with pesky acne and pimples overnight.

COSRX Acne Pimple Master Patch Amazon

8. BREYLEE Acne Treatment Serum


BreyLee’s Acne Treatment Serum uses tea tree oil and camellia sinensis leaf extract that help to remove acne and repair your skin. Also, the product features small molecules that help to undo skin damage, moisturize and shrink your pores. The light texture and mild formula of this product are non-greasy and easy to use. Use this product for three to four weeks during a mild breakout to treat acne and repair your skin. For those severe acne moments, you should use the product for two cycles or eight weeks.

BREYLEE Acne Treatment Serum Amazon

9. iUNIK Tea Tree Relief Natural Facial Serum 


For those with sensitive skin, Korean skincare brand iUnik has products that might help you out. The Tea Tree Relief Serum uses tea tree leaf water and centella asiatica leaf water to help soothe, nourish and heal your acne-prone skin. It can be used on all skin types — sensitive, normal, and aging, while also brightening and moisturizing the skin. With such simple ingredients, this product is perfect for those with skin that can’t withstand fragrance or rigorous, intrusive ingredients.

iUNIK Tea tree Relief Natural Facial Serum Amazon

10. Cystic Acne Treatment and Acne Scar Remover 


This 100% natural acne cream will help soothe, repair and renew your skin. Using ingredients like bentonite clay, aloe vera, arnica montana and tea tree oil, this cream by Aeno is potent and effective. It helps to free hair follicles from underneath your skin and helps to remove oil build-up so that the true causes of acne disappear. The cream also helps to remove acne scars by nourishing the skin to promote healing.

Cystic Acne Treatment and Acne Scar Remover Amazon

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